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Publications

2018


M. Sasikala, Ravikanth VV, Murali Manohar K, Neha Deshpande, Sandhya Singh, PavanKumar P, R. Talukdar, Sudip Ghosh, Mohsin Aslam, GV. Rao, R. Pradeep, D.Nageshwar Reddy. Bach2 repression mediates Th17 cell induced inflammation and associates with clinicalfeatures of advanced disease in chronic pancreatitis. United European Gastroenterology Journal2018, Vol. 6(2) 272–282


2017


AparnaJakkampudi, RamaiahJangala, Ratnakar Reddy, SasikalaMitnala, G Venkat Rao, RebalaPradeep, D Nageshwar Reddy, RupjyotiTalukdar. Acinar injury and early cytokine response in human acute biliary pancreatitis. Sci Rep. 2017 Nov 10;7(1):15276


Neha Deshpande, Radhika Chavan, Govardhan Bale, Urmila SteffieAvanthi, Mohsin Aslam, Mohan Ramchandani, D. Nageshwar Reddy, V. V. Ravikanth. Hereditary persistence of alpha fetoprotein is associated with -119 G>A polymorphism in AFP gene. ACG Case Rep J 2017;4:e33. doi:10.14309/crj.2017.33.


Deepesh Sharma,  Aparna Jakkampudi, Ratnakar Reddy, PanyalaBalakumar Reddy, AasishPatil, HVV Murthy, G. Venkat Rao, D. Nageshwar Reddy, RupjyotiTalukdar. Association of Systemic Inflammatory and Anti-Inflammatory Responses with Adverse Outcomes in Acute Pancreatitis: Preliminary Results of an Ongoing Study. Dig Dis Sci. 2017 Dec;62(12):3468-3478


Govardhan B, Steffie UA, Ravi Kanth VV, Rao PN, Mithun Sharma, Sasikala M, Nageshwar Reddy D. Regional differences in genetic susceptibility to NAFLD in two distinct Indian ethnicities. World Journal of Hepatology 2017;9(26): 1101–1107


Murali Manohar K, Sasikala M, Kvsrr Y, Sunil V, Talukdar R, Murthy H, Ramji C, Rao GV, PradeepR, Reddy DN.Plasma microRNA192 in combination with serum CA19-9 as non-invasive prognostic biomarker in periampullary carcinoma. Tumour Biol. 2017 Mar;39(3):1010428317695018. doi: 10.1177/1010428317695018.


Sai ManasaJandhyala, A. Madhulika, G. Deepika, G. Venkat Rao, D. Nageshwar Reddy,ChivukulaSubramanyam, MitnalaSasikala, RupjyotiTalukdar. Altered intestinal microbiota in patients with chronic pancreatitis: implications in diabetes andmetabolic abnormalities. Scientific Reports 7:43640. DOI: 10.1038/srep43640. Published: 03 March 2017


Neha Deshpande , Radhika Chavan, Govardhan Bale, Urmila SteffieAvanthi, Mohsin Aslam, Mohan Ramchandani, D. Nageshwar Reddy, V. V. Ravikanth. Hereditary persistence of alpha fetoprotein is associated with -119 G>A polymorphism in AFP gene. ACG Case reports Journal, March1,2017;


Ratnakar Reddy B, Aparna J, Sasikala M, Subramanyam C, Ramaiah J, Rao GV. Talukdar R, Reddy DN. Pancreatic stellate cell: The pandora’s box for pancreatic disease biology. World Journal of Gastroenterology2017;21;23(3):382-405


2016


K. Murali Manohar, M. Sasikala, P. Pavan Kumar, G.V. Rao, D. Nageshwar Reddy. Dysregulated miRNA associated with transcription factors of insulin gene expression in chronic pancreatitis. Journal of Endocrine and Metabolic Diseases, 2016;6:205-227


V. V. Ravi Kanth, G.V. Rao, B. Govardhan, M. Sasikala, C. Subramanyam, HVV Murthy, Siva Prasad S, Deepika G, Pradeep R, D. Nageshwar Reddy. Polymorphisms in UGT1A1 gene predispose South Indians to pigmentous gallstones. Journal of Clinical and Experimental Hepatology, 2016;6;3:216–223


Talukdar R, Lakhtakia S, Nageshwar Reddy D, Rao GV, Pradeep R, Banerjee R, Gupta R, Ramchandani M, Tandan M,Murthy HVV. Ameliorating effect of antioxidants and pregabalin combination in pain recurrence after ductal clearance in chronic pancreatitis: Results of a randomized, double blind, placebo-controlled trial. J GastroenterolHepatol. 2016 Sep;31(9):1654-62. doi: 10.1111/jgh.13332.


Talukdar R, Sareen A, Zhu H, Yuan Z, Dixit A, Cheema H, George J, Barlass U, Sah R, Garg SK, Banerjee S, Garg P,Dudeja V, Dawra R, Saluja AK. Release of Cathepsin B in Cytosol Causes Cell Death in Acute Pancreatitis. Gastroenterology. 2016 Oct;151(4):747-758.


VishnubhotlaVenkata Ravi Kanth, MitnalaSasikala, Mithun Sharma, PadakiNagaraja Rao, DuvvuruNageshwar Reddy. Genetics of non-alcoholic fatty liver disease: fromsusceptibility and nutrient interactions to management. World J Hepatol 2016 July 18; 8(20): 827-837


Neha Deshpande, V. Sharanya, V.V. Ravi Kanth, H.V.V. Murthy, M. Sasikala, Rupa Banerjee, Manu Tandan, D. Nageshwar Reddy. Rapid and ultra-rapid metabolizers with CYP2C19*17 polymorphism do not respond to standard therapy with proton pump inhibitors. Meta Gene. 2016 Jun 18;9:159-64


Aparna Jakampudi, RamaiahJangala, B Ratnakar Reddy, SasikalaMitnala, D Nageshwar Reddy, RupjyotiTalukdar. NF-kB in acute pancreatitis: Mechanisms and therapeutic potential. Pancreatology. 2016 Jul-Aug;16(4):477-88


MitnalaSasikala, RupjyotiTalukdar, ChivkulaSubramanyam and Nageshwar Reddy D The Enigma of Type 3c Diabetes inChronic Pancreatitis. Pancreas Open J. 2016;1(2): 19-21.


P. Pavan Kumar, M. Sasikala, K. Mamatha, G. V. Rao, R. Pradeep, R.Talukdar, D. Nageshwar Reddy. Characterization of Islets from Chronic Calcific Pancreatitis Patients of Tropical Region with Distinct Phenotype. Advances in Bioscience and Biotechnology, 2016, 7,1-10


RupjyotiTalukdar, SasikalaMitnala, Pavan Kumar Pondugala,Venkata Rao   Guduru, Pradeep Rebala, Nageshwar Reddy Duvvuru, T-helper cell mediated islet inflammation contributes to β-cell dysfunction in chronic pancreatitis.Pancreas. 2016 Mar;45(3):434-42


P. Pavan Kumar, G. Radhika, G.V. Rao, D. N. Reddy, M. Sasikala. Differentiation of pancreatic ductal epithelial cells in to insulin like cell clusters in chronic pancreatitis. Journal of Endocrine and Metabolic Diseases, 2015, 5, 177-183


2015


Sai ManasaJandhyala, RupjyotiTalukdar, ChivkulaSubramanyam, Harish Vuyyuru, MitnalaSasikala, D Nageshwar Reddy. Role of the normal gut microbiota. World J Gastroenterol 2015 August 7; 21(29): 8787-8803


Steffie Urmila Avanthi, VV Ravi Kanth, Jaya Agarwal, SundeepLakhtakia, KarthickGangineni, GV Rao, DN Reddy, RupjyotiTalukdar. Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India. J GastroenterolHepatol. 2015 Dec;30(12):1796-801


Mithun Sharma, PadakiNagaraja Rao, MitnalaSasikala, Mamata Reddy Kuncharam, Chima Reddy, Vardaraj Gokak, BPSS Raju, Jagdeesh R Singh, Piyal Nag, D Nageshwar Reddy Autologous mobilized peripheral blood CD34+ cell infusion in non-viral decompensated liver cirrhosis. World J Gastroenterol. 2015 Jun 21; 21(23): 7264–7271


Pavan Kumar P, M. Sasikala, GV Rao, R Pradeep, D.Nageshwar Reddy.Interferon γ decreases nuclear localization of Pdx-1 and triggers β-cell dysfunction in chronic pancreatitis. J Interferon Cytokine Res. 2015 Jul;35(7):523-9


C. Subramanyam, NiteshPratap, G. Prasad, RupjyotiTalukdar, M.Sasikala, HVV Murthy, D.Nageshwar Reddy. Influence of probiotic administration on the fecal microbiota in diarrhea-predominant irritable bowel syndrome. Indian J Gastroenterol. 2015 May;34(3):275-6


Mithun Sharma*, ShasikalaMitnala, Ravi K. Vishnubhotla ,Rathin Mukherjee, Duvvur N. Reddy, Padaki N. Rao. The Riddle of Non Alcoholic Fatty Liver Disease - Progression from NAFL to NASH. Journal of Clinical and Experimental Hepatology.2015;33(5)452


2014


V.V.  Ravikanth, M. Sasikala, PN Rao, Urmila SteffieAvanthie, K. Rajender Rao, D. Nageshwar Reddy. Pooled genetic analysis in ultrasound measured NAFLD in Indian subjects: a pilot study. World Journal of Hepatology,2014,6(6);435-442


V. V. Ravi Kanth , Sandeep Bhalsing , M. Sasikala ,G. V. Rao & R. Pradeep & Urmila SteffieAvanthi ,D. Nageshwar Reddy. Microsatellite instability and promoter hypermethylationin colorectal cancer in India. Tumour Biol. 2014 May;35(5):4347-55


R.M. Mukherj,GelliVeenaShravanti, P Balkumar Reddy, P N Rao, D N Reddy: Escalated Expressioin of Autophagy Related Gene Atg5 in Hepatitis B Virus Infection: J Microbiol Res Rev. 2(7): 68-73,2014.


V V Ravi Kanth, D Nageshwar Reddy: Role of Matrix metalloproteinases in physiological processes and disease: Indian J Med Res. 2014 Nov;140(5):585-7.


Aparna Jakkampudi , RM Mukherjee , Ramya Kota , GelliVeenaShravanti , PN Rao , DN Reddy. Downregulation of Human Toll-like Receptor 2 and 4 Genes in inactive carriers of Hepatitis B Virus Infection-a possible mode of viral persistence. J GastroenterolHepatol Res. 2014;3(4):1030-1034.


V V Ravi Kanth,  D Nageshwar Reddy: Genetics of acute and chronic pancreatitis: An update: World J GastrointestPathophysiol. 2014 Nov 15;5(4):427-37


P.N.Rao, P.Balkumar Reddy, R.M.Mukherjee, R.Gupta, D.N.Reddy. Spectrum of Incidentally Detected Hepatitis C Virus Infection in Southern India- A Prospective Study. Global Journal of Gastroenterology & Hepatology, 2014;2, 69-73.


Sadik Ali Mohammad, Shaik Sarfaraz Nawaz, Imran Ahmed Siddiqui, Sasikala M, Rathindra Mohan Mukherjee, Nagaraja Rao P, Nageshwar Reddy D. Circulating visfatin and proinflammatory cytokine levels in non alcoholic fatty liver disease. International Journal of Current Research, 2014;Vol.6, Issue.8, 8159-8162.


2013


MitnalaSasikala , GuduruVenkat Rao, VenkateshanVijayalakshmi, Rebala Pradeep, Suresh Pothani, PondugalaPavan Kumar, Radhika Gaddipati, GanneruSirisha, Ramji Cheemalakonda, ChivukulaSubramanyam,SeshadriVasudevan, D. Nageshwar Reddy. Long-term functions of encapsulated islets grafted in nonhuman primates without immunosuppression. Transplantation. 2013 Oct 15;96(7):624-32


Uma Mahesh KSS, Murali MK, Sasikala M, Talukdar R, Rao GV, Spandana B, Rajasekhar K, Siva Prasad S, Anuradha S, Ramji C, Pradeep R, Reddy DN. MicroRNA profiling in periampullarycarcioma. Pancreatology 2013; 14: 36-47


Subba Rao M, Sasikala M, DN Reddy. “Thinking outside the liver”: Induced pleuripotent stem cells for hepatic applications. World Journal of Gastroenterology,2013,19:3385-3396


Banerjee R, Balaji M, Sasikala M, Anuradha S, GV Rao, D.Nageshwar Reddy. Granulomas of intestinal tuberculosis and Crohn's disease can be differentiated by CD73 cell surface marker expression: a pilot study. Dig Dis Sci. 2013 Aug;58(8):2301-7


SiddapuramSivaprasad, Bale Govardhan, RamanjujamHarithakrishna , GuduruVenkat Rao, Rebala Pradeep, BharadhwajKunal, Nalla Ramakrishna, ShekaranAnuradha, DuvvuruNageshwar Reddy. Association of vascular endothelial growth factor (VEGF) gene polymorphism and increased serum VEGF concentration with pancreatic adenocarcinoma. Pancreatology 13 (2013) 267 – 272.


Rathindra Mohan Mukherjee, GelliVeenaShravanti, Aparna Jakkampudi, Ramya Kota, Asha LathaJangala, PanyalaBalkumar Reddy, PadakiNagaraja Rao, Rajesh Gupta, DuvvuruNageshwar Reddy. Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration. Journal of Clinical and Experimental Hepatology/2013/Vol/No. 1-7.


R.M.Mukherjee, JyothiArava, P.Balkumar Reddy, P.N.Rao, R.Gupta, D.N.Reddy. Role of Hepatitis B Virus Surface Antigen Quantification in e Antigen Negative Chronic Hepatitis B Infection. Global J. Sci. Frontier Res. 2013;Volume 13 Issue 3 Version 1.0


RM Mukherjee  ,GelliVeenaShravanti , Asha LathaJangala, PN Rao , DN Reddy.Subversion of cellular inhibitor of apoptosis protein 2 gene expression in hepatitis B virus infected peripheral blood mononuclear cells.Applied Cell Biology, 2013;2(4):144-148.


Hiba Sami, Meher Rizvi, MohdAzam, RM Mukherjee, Indu Shukla, M R Ajmal, Abida Malik. Emergence Of Hepatitis B Virus Genotype F In Aligarh Region Of North India, Advances in Virology, Volume 2013, Article ID 846849


Sadik AM, Siva Prasad S, Guru Prasad M, Sasikala M, Manu Tandan, Rupa Banerjee, Nageshwar Reddy D. Thiopurine methyltransferase as a therapeutic indicator of purine analogues: A preliminary study in southern metropolis. Int. J. Bioassays. 2013; 02(10), 1375-1379


M  Sasikala, R Talukdar, C Subramanyam, GV Rao, R Pradeep, DN Reddy. β cell     dysfunction in chronic pancreatitis. Digestive Disease Sciences, (2012) 57:1764–1772.


2012


P. Pavan Kumar, G. Radhika, G. V. Rao, R. Pradeep, C. Subramanyam, R. Talukdar, D. N. Reddy, M. Sasikala: Interferon γ and glycemic status in diabetes associated with Chronic Pancreatitis: Pancreatology 12 (2012) 65-70.


Siddapuram Siva Prasad, P. N. Rao, Rajesh Gupta, Kaitha Ashwini, DuvvuruNageshwar Reddy: The Distribution of genotype and allelic frequency of IL28B gene polymorphism in Andhra Pradesh, India. Journal of Clinical and Experimental Hepatology/ June 2012/ Vol.2/No2/ 1-4.


GelliVeenaShravanthi, R. M. Mukherjee, Aparna Jakkampudi, P. Balkumar Reddy, P. N. Rao, Rajesh Gupta and D. Nageshwar Reddy: Human RNA Methylating enzyme DNMT2 Gene Expression is down regulated in Chronic Hepatitis B Virus infection: Experimental & Clinical Hepatology, 2012; 8 (1 – 2):53-59.


GelliVeenaShravanthi, Rathindra Mohan Mukherjee, PadakiNagaraja Rao, Aparna Jakkampudi, PanyalaBalkumar Reddy, Rajesh Gupta, DuvvuruNageshwar Reddy: Reduced Expression of Human Chemokine Genes RANTES and IP-10 in Hepatitis B Virus Mediated Cirrhosis of Liver. Journal of Biology and Life Science, 2012; ISSN 2157-60762012, Vol. 3, No. 1


R. M. Mukherjee, Budhapriya Vilas Bansode, Puja Gangwal, Aparna Jakkampudi, P. Balkumar Reddy, P. N. Rao, R. Gupta, D. N. Reddy: Human Interferon Regulatory factor 2 Gene Expression is included in Chronic Hepatitis C Virus infection – A Possible Mode of Viral Persistence. Journal of Clinical and Experimental Hepatology. March 2012/Vol.1.2/No.1/1-8.


2011


Sasikala M, Surya P,Radhika G, Pavan Kumar P, R.M. Mukherjee, Rao P.N. Rao, Nageshwar  Reddy D.Identification of circulating CD90+ CD73 +cells in cirrhosis of liver. World Journal of stem cells, 2011,3 (7):63-69


P. Balkumar Reddy, R. M. Mukherjee, J. Aparna, P. N. Rao, Sasikala Mitnala, R. Gupta and D. N. Reddy.  Detection of diagnosis escape variants of Hepatitis B virus by in house polymerase chain reaction assay. J.Gen.Mol.Virol,3(3):43-48, 2011.


D N Reddy, S Siva Prasad: Genetic basis of chronic pancreatitis in Asia Pacific region: Journal of Gastroenterology and Hepatology: 26 (2011) 2-5.


Siva Prasad Siddapuram, Rupa Banerjee, Manu Tandan, NiteshPratap, Sasikala Mitnala, Nageshwar Reddy D. CYP2C polymorphism as a predictor of personalized therapy in South Indian population. Journal of Physicians of India, 2011,1-7


2010


Radhika G, M. Sasikala P. N. Rao, G. V. Rao, Pradeep rabella, Magnus Mansard, AnuradhaSekaran, and D.Nageshwar Reddy. Visceral adipose tissue visfatin in Nonalcoholic fatty liver disease: Annals of Hepatology, 2010; 9 (3):266-270.


SasikalaMitnala, Nageshwar Reddy Duvvuru, NiteshPratap, Sanjeev Kumar Sharma, Balkumar Reddy Panyala, AnuradhaSekaran, RupaBenarjee, Bhaskara Reddy Duvvuru .Absence of Mycobacterium aviumssparatuberculosis- specific IS 900 sequence in Intestinal tissues of Crohn’s disease in Indian patients. Indian Journal of Gastroenterology. 2010; 28 (5): 169-74.


R M Mukherjee, P Balkumar Reddy, JyothiArava, P N Rao, Sasikala Mitnala, R Gupta, D N Reddy: Relationship between serum HBsAg level, HBV DNA level, and peripheral immune cells in patients with chronic hepatitis B virus infection: Hepatic Medicine: Evidence and Research: 2010;(2):1-6.


Sivaprasadsiddapuram, SwapnaMahurkar, D.Nageshwar Reddy, M. Sasikala, Venkat  Rao Guduru, Pradeep Rabella, Magnus Jayaraj Mansard. Hepatic Cholesterol transporter ABCG8 Polymorphisms in Gallstone disease in Indian Population...Journal of Gastroenterology and Hepatology, 2010; 25: 1093–1098


SasikalaMitnala, Pavan Kumar Pondugala, Venkat Rao Guduru,  Pradeep Rabella, JayashreeThiyyari, SubramanyamChivukula, SadasivuduBoddupalli,  Nageshwar Reddy Duvvuru: Reduced Expression of pdx-1 is Associated with Decreased Beta Cell Function in Chronic Pancreatitis: Pancreas, 2010;39 (6):856-862.


2009


Rathindra Mohan Mukherjee, PanyalaBalkumar Reddy , MitnalaSasikala, PadakiNagaraja Rao, DuvvuruNageshwar Reddy .Identification of genotype B among Hepatitis B virus – infected patients in Hyderabad.  Ann Hepatol. 2009 Jul-Sep;8(3):269-70.


Varadaraj P. Gokak, Sasikala M, Ramji C, RupaBenerjee, Nagaraja Rao P, Nageshwar Reddy D.Hairdye induced hepatitis: an unusual cause of acute hepatitis. 2009, Saudi Journal of Gastroenterology, 2009; 15 (2): 138-139.


Joglekar M V, Deepak Patil, Vinay M. Joglekar, GV Rao, D Nageshwar Reddy, SasikalaMitnala, Yogesh Shouche and Anandwardhan A. Hardikar The miR-30 Family microRNAs Confer Epithelial Phenotype to Human Pancreatic Cells. Islets. 2009; 1(2), 1-11,


SwapnaMahurkar, D Nageshwar Reddy, G Venkat Rao, GirirajRatanChandak: Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis: World Journal of Gastroenterology: 2009; 15(3):264-269.


SwapnaMahukar, Seema Bhaskar, Nageshwar D Reddy, Swami Prakash, Venkat G Rao, Shiv Prasad Singh, Varghese Thomas, GirirajratanChandak: TCF7L2 Gene Polymorphisms do not Predict Susceptibility to Diabetes in  Tropical Calcific Pancreatitis but May Interact with SPINK1 and CTSB Mutations in Predicting Diabetes. B M C Medical Genetics: 2008; 9:80.

 

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